does nystatin need to be refrigerated

2 min read 11-03-2025

Meta Description: Is your nystatin prescription requiring refrigeration? Find out if you need to refrigerate nystatin cream, ointment, or oral suspension, plus storage tips for optimal efficacy and safety. Learn about expiration dates and what to do with expired medication.

Nystatin is a common antifungal medication used to treat various fungal infections, including thrush (oral candidiasis), vaginal yeast infections, and skin infections. But a frequently asked question surrounding its use is: does nystatin need to be refrigerated? The answer isn't a simple yes or no, as it depends on the specific formulation of nystatin. Let's break it down.

Nystatin Cream and Ointment: Refrigeration?

Generally, nystatin cream and ointment do not need to be refrigerated. They are often stable at room temperature, provided they are stored in a cool, dry place away from direct sunlight and heat. Always check the specific instructions on your medication's packaging. The manufacturer's recommendations are paramount.

Proper Storage for Topical Nystatin

Cool, Dry Place: Store your nystatin cream or ointment in a cool, dry location, away from extreme temperatures.
Avoid Direct Sunlight: Direct sunlight can degrade the medication, reducing its effectiveness.
Tightly Closed Container: Ensure the container is tightly closed to maintain its potency and prevent contamination.

Nystatin Oral Suspension: Refrigeration is Key

Unlike the topical forms, nystatin oral suspension (liquid) usually does require refrigeration. This is crucial for maintaining the medication's stability and preventing bacterial growth. The liquid formulation is more susceptible to degradation than creams or ointments.

Storing Nystatin Oral Suspension:

Refrigerate After Opening: Refrigerate the oral suspension immediately after opening the bottle.
Shake Well Before Each Dose: Because the medication can settle, always shake the bottle vigorously before each dose.
Discard After Expiration: Follow the expiration date printed on the label. Never use medication past its expiration date.

What Happens If Nystatin is Not Stored Properly?

Improper storage of nystatin, especially the oral suspension, can lead to:

Reduced Efficacy: The medication may lose its potency, making it less effective in treating your infection.
Bacterial Contamination: In the case of the oral suspension, improper storage can increase the risk of bacterial contamination. This could lead to further complications.
Changes in Appearance or Texture: You might notice changes in the color, consistency, or smell of the medication. If this occurs, discard it immediately.

Frequently Asked Questions (FAQs)

Q: My nystatin cream doesn't have any specific storage instructions. What should I do?

A: If your cream or ointment lacks specific instructions, store it in a cool, dry place away from direct sunlight and heat, as a general precaution.

Q: How long is nystatin good for after opening?

A: This varies depending on the formulation and manufacturer. Always refer to the packaging for the specific expiration date and instructions. Discard the medication after this date.

Q: Can I freeze nystatin?

A: No, freezing nystatin is not recommended. Freezing can damage the medication, rendering it ineffective.

Q: What should I do with expired nystatin?

A: Never use expired medication. Dispose of expired nystatin according to your local guidelines. Many pharmacies offer medication take-back programs.

Conclusion: Check Your Label!

The need for refrigeration with nystatin depends entirely on the formulation. Topical nystatin cream and ointment usually do not require refrigeration, while the oral suspension almost always does. Always check the specific instructions on your prescription label. If you have any questions about storing your nystatin medication, consult your pharmacist or doctor. They can offer personalized advice based on your specific situation and medication. Remember, proper storage ensures the medication's effectiveness and safety.